Regeneration is a 1915 film which tells the story of a poor orphan who rises to control the mob, until he meets a woman for whom he wants to change. It stars John McCann , James A. Marcus , Maggie Weston , H. McCoy , Rockliffe Fellowes , William Sheer , Carl Harbaugh and Anna Q. Nilsson.
It was adapted by Carl Harbaugh and Raoul Walsh from a memoir My Mamie Rose by Owen Frawley Kildare and the adapted play by Kildare and Walter C. Hackett . It was directed by Walsh. In 2000 the United States Library of Congress deemed the film "culturally significant" and selected it for preservation in the National Film Registry.