The no-huddle offense is a hurry up offense designed to minimize clock usage and or keep defenses off guard. The offense has a series of plays called in a single huddle, or from the sideline, and run those plays consecutively without going into a huddle. This keeps the defense from calling different plays to counter the situation. It also hampers the defense's ability to switch player's in and out as the offense controls the play.
It is most often used during the end of the first half or end of the game when the offense needs to score (either for momentum going into halftime, or to win the game at the end of the game). This is sometimes used to describe a Hurry-up Offense / Two-minute Drill, a formation or series of formations and plays scripted in practice and designed to score from any point on the field in under two minutes. However, the no-huddle is sometimes used by teams to take the advantage away from the defense at any point in the game.